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Enzymes are often viewed the pinnacle of what catalysis strives to be. They carry out conversion of chemicals with an elegance and selectivity that most chemists would only dream of. Yet the limitations of enzymatic catalysis are something that needs to be understood such as tolerance to a wide-range of conditions including temperature, pressure, pH and concentration gradients. The development of manufacturing methods that exploit the advantages of enzymes will be an important contribution to sustainable chemistry manufacturing.

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